Anti-HMGB1 monoclonal antibody therapy for a wide range of CNS and PNS diseases

High mobility group box-1 (HMGB1), a representative damage associated-molecular pattern (DAMP), has been reported to be involved in many inflammatory diseases. Several drugs are thought to have potential to control the translocation and secretion of HMGB1, or to neutralize extracellular HMGB1 by bin...

Full description

Bibliographic Details
Main Authors: Masahiro Nishibori, Shuji Mori, Hideo K. Takahashi
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319310515