Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies.

Genome-wide association studies (GWASs) have identified many disease associated loci, the majority of which have unknown biological functions. Understanding the mechanism underlying trait associations requires identifying trait-relevant tissues and investigating associations in a trait-specific fash...

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Bibliographic Details
Main Authors: Xingjie Hao, Ping Zeng, Shujun Zhang, Xiang Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5805369?pdf=render