Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies.
Genome-wide association studies (GWASs) have identified many disease associated loci, the majority of which have unknown biological functions. Understanding the mechanism underlying trait associations requires identifying trait-relevant tissues and investigating associations in a trait-specific fash...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5805369?pdf=render |