Early Growth Response 1-Dependent Downregulation of Matrix Metalloproteinase 9 and Mouse Double Minute 2 Attenuates Head and Neck Squamous Cell Carcinoma Metastasis

Early Growth Response 1-Dependent Downregulation of Matrix Metalloproteinase 9 and Mouse Double Minute 2 Attenuates Head and Neck Squamous Cell Carcinoma Metastasis

Background/Aims: The functional relevance of early growth response-1 (EGR1) on cancer invasion remains controversial. The effect of EGR1 on the expression of MMP9, which is important for HNSCC invasion, is still disputed. There is no previous data showing the effect of EGR1 on mouse double minute 2...

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Bibliographic Details
Main Authors: Jinkyung Kim, Sung-Min Kang, Su Young Oh, Soo Hyun Kang, Inhan Lee, Jae Chan Hwang, Heon-Jin Lee, So-Young Choi, Su-Hyung Hong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Early growth response1
Head and neck squamous cell carcinoma
Mouse double minute 2 homolog
Matrix metalloproteinases
The Cancer Genome Atlas
Online Access:https://www.karger.com/Article/FullText/494867

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https://www.karger.com/Article/FullText/494867

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