A Systematic Analysis of miRNA-mRNA Paired Variations Reveals Widespread miRNA Misregulation in Breast Cancer

MicroRNAs (miRNAs) are a class of small noncoding RNAs that can regulate gene expression by binding to target mRNAs and induce translation repression or RNA degradation. There have been many studies indicating that both miRNAs and mRNAs display aberrant expression in breast cancer. Previou...

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Bibliographic Details
Main Authors: Lei Zhong, Kuixi Zhu, Nana Jin, Deng Wu, Jianguo Zhang, Baoliang Guo, Zhaoqi Yan, Qingyuan Zhang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/291280