Molecular Dissection of Neurodevelopmental Disorder-Causing Mutations in CYFIP2

Actin remodeling is frequently regulated by antagonistic activities driving protrusion and contraction downstream of Rac and Rho small GTPases, respectively. WAVE regulatory complex (WRC), which primarily operates downstream of Rac, plays pivotal roles in neuronal morphogenesis. Recently, two indepe...

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Bibliographic Details
Main Authors: Matthias Schaks, Michael Reinke, Walter Witke, Klemens Rottner
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/6/1355