Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

Abstract Antiviral treatment options for chronic Hepatitis E Virus (HEV) infections are limited and immunological determinants of viral persistence remain largely unexplored. We studied the antiviral potency of pegylated interferon-α (pegIFNα) against HEV infections in humanized mice and modelled in...

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Bibliographic Details
Main Authors: Martijn D. B. van de Garde, Suzan D. Pas, Gertine W. van Oord, Lucio Gama, Youkyung Choi, Robert A. de Man, Andre Boonstra, Thomas Vanwolleghem
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07434-y

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https://doi.org/10.1038/s41598-017-07434-y

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