Hepatocyte growth factor modification enhances the anti-arrhythmic properties of human bone marrow-derived mesenchymal stem cells.

BACKGROUND/AIMS: Chronic myocardial infarction (MI) results in the formation of arrhythmogenic substrates, causing lethal ventricular arrhythmia (VA). We aimed to determine whether mesenchymal stem cells (MSCs) carrying a hepatocyte growth factor (HGF) gene modification (HGF-MSCs) decrease the level...

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Bibliographic Details
Main Authors: Jian Zhang, Lin-Lin Wang, Wei Du, Yi-Chao Yu, Wei-Zhu Ju, Yi-Long Man, Xiao-Rong Li, Yan Chen, Zi-Dun Wang, Wei-Juan Gu, Feng-Xiang Zhang, Hua Wang, Chu-Tse Wu, Ke-Jiang Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4216066?pdf=render