Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis.

Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis.

Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection. Here, we studied TB association and expression of 18 genes...

Full description

Bibliographic Details
Main Authors: Sonia Davila, Martin L Hibberd, Ranjeeta Hari Dass, Hazel E E Wong, Edhyana Sahiratmadja, Carine Bonnard, Bachti Alisjahbana, Jeffrey S Szeszko, Yanina Balabanova, Francis Drobniewski, Reinout van Crevel, Esther van de Vosse, Sergey Nejentsev, Tom H M Ottenhoff, Mark Seielstad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2568981?pdf=render

Internet

http://europepmc.org/articles/PMC2568981?pdf=render

Similar Items