Mitochondrial Damage-Associated Molecular Patterns of Injured Axons Induce Outgrowth of Schwann Cell Processes

Mitochondrial Damage-Associated Molecular Patterns of Injured Axons Induce Outgrowth of Schwann Cell Processes

Activated Schwann cells put out cytoplasmic processes that play a significant role in cell migration and axon regeneration. Following nerve injury, axonal mitochondria release mitochondrial damage-associated molecular patterns (mtDAMPs), including formylated peptides and mitochondrial DNA (mtDNA). W...

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Bibliographic Details
Main Authors: Andrea Korimová, Ilona Klusáková, Ivana Hradilová-Svíženská, Marcela Kohoutková, Marek Joukal, Petr Dubový
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
RT4-D6P2T schwannoma cells
in vitro
fMLP
CpG ODN
FPR2
TLR9
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00457/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00457/full

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