The anti-IRBP IgG1 and IgG2a response does not correlate with susceptibility to experimental autoimmune uveitis

The anti-IRBP IgG1 and IgG2a response does not correlate with susceptibility to experimental autoimmune uveitis

Susceptibility to experimental autoimmune uveitis (EAU) in inbred mice has been associated with a dominant Th1 response. Elevated anti-inter-photoreceptor retinoid-binding protein (anti-IRBP) IgG2a/IgG1 antibody ratios have been implicated as candidate markers to predict disease severity. In the pre...

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Bibliographic Details
Main Authors: L. Vieira de Moraes, G.A. Martins, M. Flangini, O.M. Ibañez, O.A. Sant'Anna, L.V. Rizzo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Autoimmunity
IgG1 and IgG2a isotypes
Inflammation
Genetically selected mice
Uveitis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600010

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