New Aspects of Neurotransmitter Release and Exocytosis: Involvement of Ca2+/Calmodulin-Dependent Phosphorylation of Synapsin I in Insulin Exocytosis
ABSTRACT: The exocytosis of insulin from pancreatic β-cells is closely related to intracellular elevation of Ca2+. The effects of Ca2+ may be mediated by Ca2+/calmodulin-dependent protein kinase II (CaMKII). Four subunits of CaMKII, termed α, β, γ, and δ, are encoded by distinct genes, and various i...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319326118 |