Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites

Sand flies bite mammalian hosts to obtain a blood meal, driving changes in the host inflammatory response that support the establishment of Leishmania infection. This effect is partially attributed to components of sand fly saliva, which are able to recruit and activate leukocytes. Our group has sho...

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Bibliographic Details
Main Authors: Nivea F. Luz, Thiago DeSouza-Vieira, Waldione De Castro, Aislan Carvalho Vivarini, Lais Pereira, Riam Rocha França, Paulo S. Silveira-Mattos, Diego L. Costa, Clarissa Teixeira, Claudio Meneses, Viviane S. Boaventura, Camila I. de Oliveira, Ulisses Gazos Lopes, Naomi Aronson, Bruno B. Andrade, Claudia I. Brodskyn, Jesus G. Valenzuela, Shaden Kamhawi, Valeria M. Borges
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02779/full