From Synaptic Protein to Prion: The Long and Controversial Journey of α-Synuclein

Since its discovery 30 years ago, α-synuclein (α-syn) has been one of the most studied proteins in the field of neuroscience. Dozens of groups worldwide have tried to reveal not only its role in the CNS but also in other organs. α-syn has been linked to several processes essential in brain homeostas...

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Bibliographic Details
Main Authors: Antonio Heras-Garvin, Nadia Stefanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2020.584536/full