Huntington’s Disease: A Review of the Known PET Imaging Biomarkers and Targeting Radiotracers
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by a CAG expansion mutation in the <i>huntingtin</i> gene. As a result, intranuclear inclusions of mutant huntingtin protein are formed, which damage striatal medium spiny neurons (MSNs). A review of Positron...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/3/482 |