Essential role for Schizosaccharomyces pombe pik1 in septation.

BACKGROUND:Schizosaccharomyces pombe pik1 encodes a phosphatidylinositol 4-kinase, reported to bind Cdc4, but not Cdc4(G107S). PRINCIPAL FINDINGS:Gene deletion revealed that pik1 is essential. In cells with pik1 deleted, ectopic expression of a loss-of-function allele, created by fusion to a tempera...

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Bibliographic Details
Main Authors: Jae-Sook Park, Sarah K Steinbach, Michel Desautels, Sean M Hemmingsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2704394?pdf=render