The biological function of m6A demethylase ALKBH5 and its role in human disease

Abstract Human AlkB homolog H5 (ALKBH5) is a primary m6A demethylase, which is dysregulated and acts as a biological and pharmacological role in human cancers or non-cancers. ALKBH5 plays a dual role in various cancers through regulating kinds of biological processes, such as proliferation, migratio...

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Bibliographic Details
Main Authors: Jinyan Wang, Jinqiu Wang, Quan Gu, Yajun Ma, Yan Yang, Jing Zhu, Quan’an Zhang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cancer Cell International
Subjects:
m6A
Online Access:http://link.springer.com/article/10.1186/s12935-020-01450-1