Differential HFE gene expression is regulated by alternative splicing in human tissues.

The pathophysiology of HFE-derived Hereditary Hemochromatosis and the function of HFE protein in iron homeostasis remain uncertain. Also, the role of alternative splicing in HFE gene expression regulation and the possible function of the corresponding protein isoforms are still unknown. The aim of t...

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Bibliographic Details
Main Authors: Rute Martins, Bruno Silva, Daniela Proença, Paula Faustino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3048171?pdf=render