Mutagenesis and Functional Analysis of the Pore-Forming Toxin HALT-1 from Hydra magnipapillata

Actinoporins are small 18.5 kDa pore-forming toxins. A family of six actinoporin genes has been identified in the genome of Hydra magnipapillata, and HALT-1 (Hydra actinoporin-like toxin-1) has been shown to have haemolytic activity. In this study, we have used site-directed mutagenesis to investi...

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Bibliographic Details
Main Authors: Yvonne Jing Mei Liew, Wai Tuck Soh, William Febry Jiemy, Jung Shan Hwang
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/2/407