FLT3 Amplification as Double Minute Chromosomes in a Patient with Chronic Myelomonocytic Leukemia

Double minute chromosomes (dmins) are a form of gene amplification presenting as small spherical paired chromatin bodies. Dmins are rare in hematologic malignancies and are generally associated with a poor prognosis. Some case reports identified MYC or MLL gene amplification performing as dmin in my...

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Bibliographic Details
Main Authors: Heyang Zhang, Xiaoxue Wang, Shibo Li, Xianfu Wang, Xianglan Lu, Ming Li, Hua Wang, Ying Liu, Hui Pang, Lijun Zhang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2021/9932837