miR‐107 regulates growth and metastasis of gastric cancer cells via activation of the PI3K‐AKT signaling pathway by down‐regulating FAT4

Abstract Purpose To investigate the effect of miR‐107 on the growth and metastasis of gastric cancer (GC) and elucidate the probable mechanisms. Methods The expression of miR‐107 and FAT4 in GC tissues and cells were detected using qRT‐PCR. Bioinformatics and dual luciferase reporter gene assays wer...

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Bibliographic Details
Main Authors: Li Wang, Kunkun Li, Chen Wang, Xiaoxin Shi, Huiyu Yang
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.2396