Mild Endoplasmic Reticulum Stress Protects Against Lipopolysaccharide-Induced Astrocytic Activation and Blood-Brain Barrier Hyperpermeability

Mild Endoplasmic Reticulum Stress Protects Against Lipopolysaccharide-Induced Astrocytic Activation and Blood-Brain Barrier Hyperpermeability

Recent research has revealed that uncontrolled chronic neuroinflammation is closely associated with diverse neurodegenerative diseases, by impairing blood-brain barrier (BBB) function and astrocytic reaction. Endoplasmic reticulum (ER) stress is conventionally linked to the loss of neuronal structur...

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Bibliographic Details
Main Authors: Yiwei Wang, Yinan Chen, Qin Zhou, Jiawen Xu, Qingqing Qian, Pengfei Ni, Yanning Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
endoplasmic reticulum stress
astrocytes
hormesis
blood-brain barrier
neuroinflammation
neurodegeneration
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00222/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00222/full

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