Activity of trifluoperazine against replicating, non-replicating and drug resistant M. tuberculosis.

Trifluoperazine, a known calmodulin antagonist, belongs to a class of phenothiazine compounds that have multiple sites of action in mycobacteria including lipid synthesis, DNA processes, protein synthesis and respiration. The objective of this study is to evaluate the potential of TFP to be used as...

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Bibliographic Details
Main Authors: Meeta J Advani, Imran Siddiqui, Pawan Sharma, Hemalatha Reddy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22952939/?tool=EBI