A combined Activity of Thrombin and P-Selectin Is Essential for Platelet Activation by Pancreatic Cancer Cells

A combined Activity of Thrombin and P-Selectin Is Essential for Platelet Activation by Pancreatic Cancer Cells

Pancreatic cancer patients have an elevated risk of suffering from venous thrombosis. Among several risk factors that contribute to hypercoagulability of this malignancy, platelets possess a key role in the initiation of clot formation. Although single mechanisms of platelet activation are well-know...

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Bibliographic Details
Main Authors: Reza Haschemi, Lukas Maria Gockel, Gerd Bendas, Martin Schlesinger
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
dense granule release
hypercoagulability
platelets
pancreatic cancer
platelet aggregation
P-selectin
Online Access:https://www.mdpi.com/1422-0067/22/7/3323

Internet

https://www.mdpi.com/1422-0067/22/7/3323

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