Transcriptome Analysis of Porphyrin-Accumulated and X-Ray-Irradiated Cell Cultures under Limited Proliferation and Non-Lethal Conditions

Transcriptome Analysis of Porphyrin-Accumulated and X-Ray-Irradiated Cell Cultures under Limited Proliferation and Non-Lethal Conditions

5-Aminolevulinic acid (ALA) is a precursor of the photosensitizer used in photodynamic therapy. It accumulates in tumor cells and subsequently metabolizes to protoporphyrin IX (PpIX), which generates singlet oxygen after light irradiation. PpIX enhances the generation of reactive oxygen species foll...

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Bibliographic Details
Main Authors: Junko Takahashi, Masaki Misawa, Hitoshi Iwahashi
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Microarrays
Subjects:
radiotherapy
X-ray
sensitizer
photodynamic therapy
5-aminolevulinic acid (ALA)
protoporphyrin IX (PpIX)
cancer
microarray
Online Access:http://www.mdpi.com/2076-3905/4/1/25

Internet

http://www.mdpi.com/2076-3905/4/1/25

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