Proteomic fingerprints of damage in extracellular matrix assemblies
In contrast to the dynamic intracellular environment, structural extracellular matrix (ECM) proteins with half-lives measured in decades, are susceptible to accumulating damage. Whilst conventional approaches such as histology, immunohistochemistry and mass spectrometry are able to identify age- and...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-02-01
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Series: | Matrix Biology Plus |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590028520300089 |