Sequence and Structure Properties Uncover the Natural Classification of Protein Complexes Formed by Intrinsically Disordered Proteins via Mutual Synergistic Folding

Sequence and Structure Properties Uncover the Natural Classification of Protein Complexes Formed by Intrinsically Disordered Proteins via Mutual Synergistic Folding

Intrinsically disordered proteins mediate crucial biological functions through their interactions with other proteins. Mutual synergistic folding (MSF) occurs when all interacting proteins are disordered, folding into a stable structure in the course of the complex formation. In these cases, the fol...

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Bibliographic Details
Main Authors: Bálint Mészáros, László Dobson, Erzsébet Fichó, István Simon
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
intrinsically disordered protein
idp
protein–protein interaction
mutual synergistic folding
coupled folding and binding
structural analysis
structure-based classification
fold recognition
Online Access:https://www.mdpi.com/1422-0067/20/21/5460

Internet

https://www.mdpi.com/1422-0067/20/21/5460

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