The Use of Chimeric Virus-like Particles Harbouring a Segment of Hantavirus Gc Glycoprotein to Generate a Broadly-Reactive Hantavirus-Specific Monoclonal Antibody

The Use of Chimeric Virus-like Particles Harbouring a Segment of Hantavirus Gc Glycoprotein to Generate a Broadly-Reactive Hantavirus-Specific Monoclonal Antibody

Monoclonal antibodies (MAbs) against viral glycoproteins have important diagnostic and therapeutic applications. In most cases, the MAbs specific to viral glycoproteins are raised against intact virus particles. The biosynthesis of viral glycoproteins in heterologous expression systems such as bacte...

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Bibliographic Details
Main Authors: Aurelija Zvirbliene, Indre Kucinskaite-Kodze, Ausra Razanskiene, Rasa Petraityte-Burneikiene, Boris Klempa, Rainer G. Ulrich, Alma Gedvilaite
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Viruses
Subjects:
hantavirus
Gc glycoprotein
monoclonal antibody
yeast expression system
chimeric virus-like particles
Online Access:http://www.mdpi.com/1999-4915/6/2/640

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http://www.mdpi.com/1999-4915/6/2/640

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