A novel hot-plate test sensitive to hyperalgesic stimuli and non-opioid analgesics

It is widely accepted that the classical constant-temperature hot-plate test is insensitive to cyclooxygenase inhibitors. In the current study, we developed a variant of the hot-plate test procedure (modified hot-plate (MHP) test) to measure inflammatory nociception in freely moving rats and mice. F...

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Bibliographic Details
Main Authors: T.R. Lavich, R.S.B. Cordeiro, P.M.R. Silva, M.A. Martins
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300016