Collagenase treatment of cartilaginous matrix promotes fusion of adjacent cartilage
In articular cartilage-repair, grafts usually fuse unsatisfactorily with surrounding host cartilage. Enzymatic dissociation of cartilaginous matrix to free chondrocytes may benefit fusion. We tested such a hypothesis with human cartilage in vitro, and with porcine cartilage in vivo. Human articular...
Main Authors: | Ching-Chuan Jiang, Chang-Hsun Hsieh, Chun-Jen Liao, Wen-Hsiang Chang, Wei-Ju Liao, Jyy-Jih Tsai-Wu, Hongsen Chiang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | Regenerative Therapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352320420300602 |
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