Collagenase treatment of cartilaginous matrix promotes fusion of adjacent cartilage

In articular cartilage-repair, grafts usually fuse unsatisfactorily with surrounding host cartilage. Enzymatic dissociation of cartilaginous matrix to free chondrocytes may benefit fusion. We tested such a hypothesis with human cartilage in vitro, and with porcine cartilage in vivo. Human articular...

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Bibliographic Details
Main Authors: Ching-Chuan Jiang, Chang-Hsun Hsieh, Chun-Jen Liao, Wen-Hsiang Chang, Wei-Ju Liao, Jyy-Jih Tsai-Wu, Hongsen Chiang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300602