Comparative Effects of R- and S-equol and Implication of Transactivation Functions (AF-1 and AF-2) in Estrogen Receptor-Induced Transcriptional Activity

Comparative Effects of R- and S-equol and Implication of Transactivation Functions (AF-1 and AF-2) in Estrogen Receptor-Induced Transcriptional Activity

Equol, one of the main metabolites of daidzein, is a chiral compound with pleiotropic effects on cellular signaling. This property may induce activation/inhibition of the estrogen receptors (ER) a or b, and therefore, explain the beneficial/deleterious effects of equol on estrogen-dependent diseases...

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Bibliographic Details
Main Authors: Mylène Potier, Catherine Bennetau-Pelissero, Gilles Flouriot, Charlotte Carreau, Svitlana Shinkaruk
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Nutrients
Subjects:
equol
enantiomeric forms
estrogen receptor
transactivation function
phytoestrogens
Online Access:http://www.mdpi.com/2072-6643/2/3/340/

Internet

http://www.mdpi.com/2072-6643/2/3/340/

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