The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation
As a potent radiosensitizer nitric oxide (NO) may be a putative adjuvant in the treatment of malignant gliomas which are known for their radio- and chemoresistance. The NO donor prodrug JS-K (O2-(2.4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1,2-diolate) allows cell-type spec...
Main Authors: | Max Heckler, Nadja Osterberg, Jessica Guenzle, Nina Kristin Thiede-Stan, Wilfried Reichardt, Claudia Weidensteiner, Joseph E Saavedra, Astrid Weyerbrock |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-06-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317703922 |
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