Pantoprazole impairs fracture healing in aged mice

Abstract Proton pump inhibitors (PPIs) belong to the most common medication in geriatric medicine. They are known to reduce osteoclast activity and to delay fracture healing in young adult mice. Because differentiation and proliferation in fracture healing as well as pharmacologic actions of drugs m...

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Bibliographic Details
Main Authors: Maximilian M. Menger, Philipp Bremer, Claudia Scheuer, Mika F. Rollmann, Benedikt J. Braun, Steven C. Herath, Marcel Orth, Thomas Später, Tim Pohlemann, Michael D. Menger, Tina Histing
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79605-3