Vancomycin concentrations in the cervical spine after intravenous administration: results from an experimental pig study
Background and purpose — Vancomycin may be an important drug for intravenous perioperative antimicrobial prophylaxis in spine surgery. We assessed single-dose vancomycin intervertebral disc, vertebral cancellous bone, and subcutaneous adipose tissue concentrations using microdialysis in a pig model....
Main Authors: | Mats Bue, Pelle Hanberg, Mikkel Tøttrup, Maja B Thomassen, Hanne Birke-Sørensen, Theis M Thillemann, Torben L Andersson, Kjeld Søballe |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-11-01
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Series: | Acta Orthopaedica |
Online Access: | http://dx.doi.org/10.1080/17453674.2018.1501548 |
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