Vancomycin concentrations in the cervical spine after intravenous administration: results from an experimental pig study

Background and purpose — Vancomycin may be an important drug for intravenous perioperative antimicrobial prophylaxis in spine surgery. We assessed single-dose vancomycin intervertebral disc, vertebral cancellous bone, and subcutaneous adipose tissue concentrations using microdialysis in a pig model....

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Bibliographic Details
Main Authors: Mats Bue, Pelle Hanberg, Mikkel Tøttrup, Maja B Thomassen, Hanne Birke-Sørensen, Theis M Thillemann, Torben L Andersson, Kjeld Søballe
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Acta Orthopaedica
Online Access:http://dx.doi.org/10.1080/17453674.2018.1501548