Concerning RNA-guided gene drives for the alteration of wild populations

Concerning RNA-guided gene drives for the alteration of wild populations

Gene drives may be capable of addressing ecological problems by altering entire populations of wild organisms, but their use has remained largely theoretical due to technical constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a genera...

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Bibliographic Details
Main Authors: Kevin M Esvelt, Andrea L Smidler, Flaminia Catteruccia, George M Church
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-07-01
Series:eLife
Subjects:
gene drive
ecological engineering
population engineering
cas9
CRISPR
emerging technology
Online Access:https://elifesciences.org/articles/03401

Internet

https://elifesciences.org/articles/03401

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