The role of astrocytes in CNS tumours: pre-clinical models and novel imaging approaches

Brain metastasis is a significant clinical problem, yet the mechanisms governing tumour cell extravasation across the blood-brain barrier and CNS colonisation are unclear. Astrocytes are increasingly implicated in the pathogenesis of brain metastasis but in vitro work suggests both tumoricidal and t...

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Bibliographic Details
Main Authors: Emma R O'Brien, Clare eHowarth, Nicola R Sibson
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
MRI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00040/full