The role of astrocytes in CNS tumours: pre-clinical models and novel imaging approaches
Brain metastasis is a significant clinical problem, yet the mechanisms governing tumour cell extravasation across the blood-brain barrier and CNS colonisation are unclear. Astrocytes are increasingly implicated in the pathogenesis of brain metastasis but in vitro work suggests both tumoricidal and t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-04-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00040/full |