Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice

Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice

To determine the physiological role of apolipoprotein (apo) A-IV, knockout mice were created by gene targeting in embryonic stem cells. In apoA-IV knockout mice, plasma cholesterol and triglyceride levels were reduced 25% and 44%, respectively, compared with controls. These changes were accounted fo...

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Bibliographic Details
Main Authors: P H Weinstock, C L Bisgaier, T Hayek, K Aalto-Setala, E Sehayek, L Wu, P Sheiffele, M Merkel, A D Essenburg, J L Breslow
Format: Article
Language:English
Published: Elsevier 1997-09-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520371534

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http://www.sciencedirect.com/science/article/pii/S0022227520371534

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