Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance
Intensive insulin therapy can prevent or slow the progression of long-term diabetes complications but, at the same time, it increases the risk for episodes of severe hypoglycemia. In our study, we used a protocol intended to mimic the levels of blood glucose that occur in type 1 diabetic patients un...
Main Authors: | Susana Cardoso, Renato X. Santos, Sónia C. Correia, Cristina Carvalho, Maria S. Santos, Inês Baldeiras, Catarina R. Oliveira, Paula I. Moreira |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-01-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996112002951 |
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