Novel epitopes identified from efflux pumps of Mycobacterium tuberculosis could induce cytotoxic T lymphocyte response

Overcoming drug-resistance is one of the major challenges to control tuberculosis (TB). The up-regulation of efflux pumps is one common mechanism that leads to drug-resistance. Therefore, immunotherapy targeting these efflux pump antigens could be promising strategy to be combined with current chemo...

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Bibliographic Details
Main Authors: Ming-xia Zhai, Fei Chen, Yuan-yuan Zhao, Ya-hong Wu, Guo-dong Li, Yan-feng Gao, Yuan-ming Qi
Format: Article
Language:English
Published: PeerJ Inc. 2015-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1229.pdf