SOLUBILITY OF A NEW ANTIRETROVIRAL DRUG (CRS 74) IN AQUEOUS ETHANOL MIXTURES

Abstract This study concerns a new antiretroviral drug named CRS 74, which has a limited bioavailability because of its low aqueous solubility and dissolution rate. To improve these properties, CRS 74 can be recrystallized by using Liquid Anti-Solvent (LAS) crystallization. Ethanol is chosen as the...

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Bibliographic Details
Main Authors: S. P. Lacerda, J. J. Letourneau, F. Espitalier, M. I. Ré
Format: Article
Language:English
Published: Brazilian Society of Chemical Engineering
Series:Brazilian Journal of Chemical Engineering
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322016000401073&lng=en&tlng=en