SOLUBILITY OF A NEW ANTIRETROVIRAL DRUG (CRS 74) IN AQUEOUS ETHANOL MIXTURES
Abstract This study concerns a new antiretroviral drug named CRS 74, which has a limited bioavailability because of its low aqueous solubility and dissolution rate. To improve these properties, CRS 74 can be recrystallized by using Liquid Anti-Solvent (LAS) crystallization. Ethanol is chosen as the...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Brazilian Society of Chemical Engineering
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Series: | Brazilian Journal of Chemical Engineering |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322016000401073&lng=en&tlng=en |