Cell Polarity, Epithelial-Mesenchymal Transition, and Cell-Fate Decision Gene Expression in Ductal Carcinoma In Situ

Loss of epithelial cell identity and acquisition of mesenchymal features are early events in the neoplastic transformation of mammary cells. We investigated the pattern of expression of a selected panel of genes associated with cell polarity and apical junction complex or involved in TGF-β-mediated...

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Bibliographic Details
Main Authors: Danila Coradini, Patrizia Boracchi, Federico Ambrogi, Elia Biganzoli, Saro Oriana
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Surgical Oncology
Online Access:http://dx.doi.org/10.1155/2012/984346