Modulation of Circadian Rhythm of DNA Synthesis in Tumor Cells by Inhibiting Platelet-Derived Growth Factor Signaling

Circadian synchronization of cell proliferation is observed not only in normal healthy tissues but also in malignant solid tumors. However, the proliferation rhythm of tumor cells is often different from that of normal cells. We reported here that the peculiar rhythm of tumor cell proliferation was...

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Bibliographic Details
Main Authors: Hiroo Nakagawa, Satoru Koyanagi, Yukako Kuramoto, Akiko Yoshizumi, Naoya Matsunaga, Hiroshi Shimeno, Shinji Soeda, Shigehiro Ohdo
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313921