Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis
Abstract Background P-glycoprotein (P-gp) plays a critical role in protection of the intestinal epithelia by mediating efflux of drugs/xenobiotics from the intestinal mucosa into the gut lumen. Recent studies bring to light that P-gp also confers a critical link in communication between intestinal m...
Main Authors: | Sage E. Foley, Christine Tuohy, Merran Dunford, Michael J. Grey, Heidi De Luca, Caitlin Cawley, Rose L. Szabady, Ana Maldonado-Contreras, Jean Marie Houghton, Doyle V. Ward, Randall J. Mrsny, Beth A. McCormick |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | Microbiome |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40168-021-01137-3 |
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