Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis

Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis

Abstract Background P-glycoprotein (P-gp) plays a critical role in protection of the intestinal epithelia by mediating efflux of drugs/xenobiotics from the intestinal mucosa into the gut lumen. Recent studies bring to light that P-gp also confers a critical link in communication between intestinal m...

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Bibliographic Details
Main Authors: Sage E. Foley, Christine Tuohy, Merran Dunford, Michael J. Grey, Heidi De Luca, Caitlin Cawley, Rose L. Szabady, Ana Maldonado-Contreras, Jean Marie Houghton, Doyle V. Ward, Randall J. Mrsny, Beth A. McCormick
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Microbiome
Subjects:
P-glycoprotein
Multi-drug resistance transporter
Endocannabinoid
Inflammatory bowel diseases
Ulcerative colitis
Inflammation
Online Access:https://doi.org/10.1186/s40168-021-01137-3

Internet

https://doi.org/10.1186/s40168-021-01137-3

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