Computational modeling of 4-Phenoxynicotinamide and 4-Phenoxypyrimidine-5-carboxamide derivatives as potent anti-diabetic agent against TGR5 receptor

Computational study was carried out to develop a Quantitative structure-activity relationship (QSAR) model and molecular docking studies on 4-Phenoxynicotinamide and 4-Phenoxypyrimidine-5-carboxamide derivatives as potent anti-diabetic agent. Chemical structure of these molecules were optimized with...

Full description

Bibliographic Details
Main Authors: Shola Elijah Adeniji, David Ebuka Arthur, Adedirin Oluwaseye
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of King Saud University: Science
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364718302428