Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

Sepsis and septic shock are among the leading causes of death in intensive care units worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the inflammatory network leading to tissue damage, organ failure, and ultimately, death. Cytokines are important pleiotropic regula...

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Bibliographic Details
Main Authors: Wibke Schulte, Jürgen Bernhagen, Richard Bucala
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/165974