Age-associated decrease in de novo donor-specific antibodies in renal transplant recipients reflects changing humoral immunity

Age-associated decrease in de novo donor-specific antibodies in renal transplant recipients reflects changing humoral immunity

Abstract Background Older age at organ transplantation is associated with increased risk of infection and malignancy but reduced risk of cellular rejection. De novo donor-specific anti-HLA antibodies (dnDSA), are key biomarkers associated with reduced long-term allograft survival, yet there is a lac...

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Bibliographic Details
Main Authors: Seraina von Moos, Gesa Schalk, Thomas F. Mueller, Guido Laube
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Immunity & Ageing
Subjects:
De novo donor specific antibodies
Aging
Older kidney transplant recipients
Pediatric kidney transplant recipients
Immunosenescence
Online Access:http://link.springer.com/article/10.1186/s12979-019-0149-8

Internet

http://link.springer.com/article/10.1186/s12979-019-0149-8

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