Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphatase.

Exotoxins, including the hemolysins known as the alpha (alpha) and beta (beta) toxins, play an important role in the pathogenesis of Staphylococcus aureus infections. A random transposon library was screened for S. aureus mutants exhibiting altered hemolysin expression compared to wild type. Transpo...

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Main Authors: Kellie Burnside, Annalisa Lembo, Melissa de Los Reyes, Anton Iliuk, Nguyen-Thao Binhtran, James E Connelly, Wan-Jung Lin, Byron Z Schmidt, Anthony R Richardson, Ferric C Fang, Weiguo Andy Tao, Lakshmi Rajagopal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2884019?pdf=render