Akt/Bad signaling and motor neuron survival after spinal cord injury

The serine–threonine kinase Akt is a cell survival signaling pathway that inactivates the proapoptotic BCL-2 family protein Bad and promotes cell survival in cerebral ischemia. Involvement of the Akt/Bad signaling pathway after spinal cord injury (SCI) is, however, uncertain. Our results showed that...

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Bibliographic Details
Main Authors: Fengshan Yu, Taku Sugawara, Carolina M. Maier, Lily B. Hsieh, Pak H. Chan
Format: Article
Language:English
Published: Elsevier 2005-11-01
Series:Neurobiology of Disease
Subjects:
Akt
Bad
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610500118X